About the Therapy

There is no cure for cluster headache. Current treatments to relieve symptoms include preventive and acute abortive drugs such as injectable medications and inhaled oxygen. As some patients are not candidates for these medications, and others may experience significant side effects or have risk factors that prevent taking these medications, there has been a considerable need for a new treatment option.

The sphenopalatine ganglion (SPG) is a nerve bundle located deep in the face, behind the root of the nose. It is part of the autonomic nervous system. For over 100 years, the SPG has been a clinical target for procedures for pain relief. Various methods of SPG modulation have been tried but unfortunately, the headache relief associated with these procedures is often transient, some of the procedures are destructive and irreversible, and long-term relief requires repeat procedures.

Stimulation of the SPG with the Pulsante™ SPG Microstimulator System offers a reversible and adjustable option to control the debilitating pain of cluster headache. This neuromodulation solution is thought to interrupt and block the nerve signals that are thought to be responsible for generating and maintaining the pain and autonomic symptoms associated with cluster headache. Published data from the Pathway CH-1 Study, a randomized, sham-controlled, multi-center trial showed that electrically stimulating the SPG with the Pulsante™ SPG Microstimulator System is highly effective in treating cluster headache.1

Click here to learn more about the Pulsante™ SPG Microstimulator System, or here to read the full Pathway CH-1 publication.

1 Schoenen J, Jensen RH, Lantéri-Minet M, Láinez MJA, Gaul C, Goodman AM, Caparso A, May. A. Stimulation of the sphenopalatine ganglion (SPG) for cluster headache treatment. Pathway CH-1: A randomized, sham-controlled study. Cephalalgia 2013;33:816-30.
SPG

Stimulation of the SPG offers a targeted, reversible and adjustable option to control the debilitating pain of cluster headache.

 
© 2012-2015 Autonomic Technologies, Inc. All Rights Reserved. Last updated: 08 January 2015
CE Marked Intended Use: The Pulsante™ SPG Microstimulator System (ATI Neurostimulation System) is CE marked in Europe and is intended to relieve the acute pain of cluster headache. In some patients the use of the System has been associated with a reduction in the number of cluster headaches.
In the United States please note: Caution–Investigational device; limited by US law to investigational use.